Botox® (onabotulinumtoxinA) is a neuromodulator used in the medical field for a variety of purposes. In dermatology it is used to treat fine lines and wrinkles on the face. Areas commonly treated include the forehead, glabella, and around the orbit (crowes feet). The botulinum toxin is placed in the muscle very precisely and in small amounts. It acts at the neuromuscular junction to weaken the connection between the nerve ending and the muscle. By weakening this connection the muscle cannot be contracted to wrinkle the overlying skin. It is important to know that it is temporary and only last around 3 months. There are different types of botulinum toxin but they all act similarly. AbobotulinumtoxinA (Dysport®), incobotulinumtoxinA (Xeomin®), and prabotulinumtoxinA (Jeuveau®) are the commonly used types in dermatology.